Tivic Health Systems Inc. is a health tech company specializing in bioelectronic medicine and immunotherapeutics. It develops and commercializes innovative treatments focused on restoring healthy immune system function through TLR5 biologics programs and non-invasive cervical vagus nerve stimulation devices. The company's lead drug candidate, Entolimod, targets Acute Radiation Syndrome by activating innate immune pathways to prevent cell death in bone marrow and epithelial tissues. Its pipeline also includes applications for Neutropenia, lymphocyte exhaustion, and Entolasta, an optimized variant for chronic conditions. Previously known for the ClearUP device treating sinus and nasal inflammation, Tivic sells products via direct-to-consumer channels including its websites, Amazon.com, Walmart.com, BestBuy, and FSAStore, as well as through distributors. Additionally, it operates Velocity Bioworks, a subsidiary providing contract development and manufacturing services to biotech firms while supporting its own pipeline for enhanced supply chain control. Incorporated in 2016 and headquartered in Fremont, California, Tivic Health Systems Inc. plays a role in advancing immunomodulation therapies and biomanufacturing in the healthcare sector.